Our publications
Independent Research. Better Clinical Practice.
High level of clinical inertia in insulin initiation in type 2 diabetes across Central and South-Eastern Europe: insights from SITIP study
Study of Insulin Therapy initiation in Type2Diabetes in Routine Clinical Practice.
When should insulin therapy begin — and when does it, in practice?
SITIP surveyed diabetes specialists and endocrinologists across 8+ countries to answer this question with real-world data. Results indicate a consistent and measurable gap between guideline recommendations and everyday clinical decisions: only 9.4% of physicians initiate insulin at the evidence-based HbA1c threshold of 7–7.9%, while 47.4% wait until ≥9.0% is reached.
These findings support the case for targeted, independent CME — and point directly toward where education can have the greatest clinical impact.
Link to published article: Acta Diabetologia Journal
Omega-3 polyunsaturated fatty acids favourably modulate cardiometabolic biomarkers in type 2 diabetes: a meta-analysis and meta-regression of randomized controlled trials
Our study reports a major new indication for n-3PUFA intake: improvement in lipid profile and markers of inflammation without adverse effects on LDL or HbA1c. Neither duration of supplementation nor dosage of n-3PUFAs statistically explain the observed heterogeneity meaning that optimal treatment patterns for clinical practice are yet to be determined and further research is warranted. Future precision medicine trials should aim to establish whether interactions between n-3PUFAs and cardiometabolic biomarkers are modified by patient level characteristics to improve response to supplementation in T2DM and whether such improvements are observed in T1DM.
Link to published article: Cardiovascular Diabetology Journal
Impact of ideal cardiovascular health in childhood on the retinal microvasculature in mid adulthood: The cardiovascular risk in young Finns study
Poster at EASD 2017 in Lisbon.
Cardiovascular health and ideal CVH from childhood to adulthood appear to have protective effect on the retinal microvasculature.
Link to conference of poster presentation: EASD